HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 2-chloro-6-methyl-5H,6H,7H-pyrrolo(3,4-b)pyridin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 2-Pyridinecarboxylic acid, 3-(bromomethyl)-6-chloro-, methyl ester | HCID 58216631 | — |
| Product | 2-chloro-6-methyl-5H,6H,7H-pyrrolo(3,4-b)pyridin-7-one | HCID 58216659 | — |
Reaction Steps
2-Chloro-6-methyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one was prepared according to the general procedure in Example 7 Step 1 using methyl 3-(bromomethyl)-6-chloropyridine-2-carboxylate (0.40 g, 1.49 mmol) and methylamine, 2 M in THF (10 mL, 20 mmol) as the starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344144B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-87ff2f77baeb4e97b85b6ddc2fa51845 |
| Source note | uspto-grants-2013_01 |