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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1799561Generated: October 31, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 58216623, compound

https://huagongshe.com/reaction/1799561

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ReactantHCID 86652371HCID 86652371—
ProductHCID 58216623HCID 58216623—

Reaction Steps

The title compound was prepared as described in Example 1 Step 5 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (150 mg, 0.48 mmol), and 1-(5-chloro-1H-imidazo[4,5-b]pyridin-2-yl)ethanol (95 mg, 0.48 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08344144B2
Source datasetuspto-grants-2013_01
ORD IDord-fad6d5003b444bc380d649613516feab
Source noteuspto-grants-2013_01