4-Morpholineacetic acid → HCID 86652372, compound

HRID 1799562Notes

Reaction equation

HRID 1799562 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([NH2:9])=[CH:4][CH:3]=1.[N:10]1([CH2:16][C:17](O)=O)[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1>>[Cl:1][C:2]1[N:7]=[C:6]2[N:8]=[C:17]([CH2:16][N:10]3[CH2:15][CH2:14][O:13][CH2:12][CH2:11]3)[NH:9][C:5]2=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 4389684-Morpholineacetic acidHCID 106306156-Chloropyridine-2,3-diamine

Product 1

HCID 86652372HCID 86652372, compound

Procedure

The title compound was prepared as described in Example 23, Step 2 using 6-chloropyridine-2,3-diamine (650 mg, 4.53 mmol) (Example 23, Step 1) and morpholin-4-ylacetic acid (660 mg, 4.53 mmol) as starting materials.

Sources & evidence

ORD record
ord-65d04670f4fd499486591118ab365f05
Source dataset
uspto-grants-2013_01
Patent number
US08344144B2

Reaction notes

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