HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2-Bromo-1,3-thiazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Ethyl 2-bromo-1,3-thiazole-4-carboxylate | HCID 353965 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Bromo-1,3-thiazole-4-carboxamide | HCID 45789632 | — |
Reaction Steps
THF (10 ml) and 20 ml of 30% aqueous ammonia were added to 1.51 g of 2-bromo-4-ethoxycarbonylthiazole, and the mixture was stirred at room temperature for 3 days. The reaction solution was concentrated to give 1.31 g of 2-bromo-4-carbamoylthiazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344154B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-dade9e0c2d084722af1b14e1ef509005 |
| Source note | uspto-grants-2013_01 |