HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)-5-methyl-1,3-dioxol-2-one → HCID 69469394, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)-5-methyl-1,3-dioxol-2-one | HCID 10774141 | — |
| Reactant | Sodium (1r,5s,6s)-6-((1r)-1-hydroxyethyl)-2-[[(z)-2-(4-hydroxymethyl-thiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate | HCID 23676797 | — |
| Product | HCID 69469394 | HCID 69469394 | 79.7% |
Reaction Steps
In the same manner as in Example 81, 156 mg of the title compound was prepared from 160 mg of sodium (1R,5S,6S)-6-((1R)-1-hydroxyethyl)-2-[[(Z)-2-(4-hydroxymethylthiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate and 122 mg of (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl bromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344154B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-7559608c6c0a4ac482c2356f4539e451 |
| Source note | uspto-grants-2013_01 |