HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium (1r,5s,6s)-6-((1r)-1-hydroxyethyl)-2-[[(z)-2-(4-hydroxymethyl-thiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate → HCID 69467318, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium (1r,5s,6s)-6-((1r)-1-hydroxyethyl)-2-[[(z)-2-(4-hydroxymethyl-thiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate | HCID 23676797 | — |
| Reactant | HCID 87089903 | HCID 87089903 | — |
| Product | HCID 69467318 | HCID 69467318 | 84.4% |
Reaction Steps
In the same manner as in Example 81, 179 mg of the title compound was prepared from 159 mg of sodium (1R,5S,6S)-6-((1R)-1-hydroxyethyl)-2-[[(Z)-2-(4-hydroxymethylthiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate and 135 mg of N,N-di(propan-1-yl)aminocarbonyloxymethyl iodide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344154B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-1c4279eb7e6a4cd0a4c7f093ff746e30 |
| Source note | uspto-grants-2013_01 |