HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S)- → 3-isopropyl-1-methyl-1H-1,2,4-triazol-5(4H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S)- | HCID 18462 | — |
| Reactant | 2-Isobutyryl-1-methylhydrazinecarboxamide | HCID 58204774 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-isopropyl-1-methyl-1H-1,2,4-triazol-5(4H)-one | HCID 136057924 | — |
Reaction Steps
2-Isobutyryl-1-methylhydrazinecarboxamide was cyclized with 10-camphorsulfonic acid at reflux in ethylacetate to give 3-isopropyl-1-methyl-1H-1,2,4-triazol-5(4H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08343955B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-0bc4f12682e148a38515885d692a22d7 |
| Source note | uspto-grants-2013_01 |