Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | Isobutylene oxide | HCID 11208 | — |
| Reactant | HCID 178506559 | HCID 178506559 | — |
| Product | HCID 58204348 | HCID 58204348 | 71% |
Reaction Steps
A mixture of 4-iodo-1H-imidazole, Cs2CO3 in 2,2-dimethyl oxirane was stirred at 120° C. for 20 min under irradiation with microwave. The reaction mixture was concentrated, and purified to give 1-(4-iodo-1H-imidazol-1-yl)-2-methylpropan-2-ol (Yield=71%). LC-MS: m/z=266 [M+H+] 1H NMR (CDCl3, 400 MHz): δ7.36 (s, 1H), 7.06 (s, 1 H), 3.84 (s, 2H), 1.22 (s, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08343955B2 |
|---|
| Source dataset | uspto-grants-2013_01 |
|---|
| ORD ID | ord-ee30d4011e014ad8a9081e5887b7ffcf |
|---|
| Source note | uspto-grants-2013_01 |
|---|
