HCID 67050682, compound → HCID 58204898, compound

HRID 1800076Notes

Reaction equation

HRID 1800076 reaction equation
Br[C:2]1[CH:25]=[CH:24][C:5]2[C:6]3[N:7]([CH:11]=[C:12]([C:14]4[N:18]([CH:19]([CH3:21])[CH3:20])[N:17]=[C:16]([NH:22][CH3:23])[N:15]=4)[N:13]=3)[CH2:8][CH2:9][O:10][C:4]=2[CH:3]=1>[Pd]>[N:13]1[C:12]([C:14]2[N:18]([CH:19]([CH3:20])[CH3:21])[N:17]=[C:16]([NH:22][CH3:23])[N:15]=2)=[CH:11][N:7]2[C:6]=1[C:5]1[CH:24]=[CH:25][CH:2]=[CH:3][C:4]=1[O:10][CH2:9][CH2:8]2

Participants

3

Reactant 1

HCID 67050682HCID 67050682, compound

Product 1

HCID 58204898HCID 58204898, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

5-(9-bromo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-2-yl)-1-isopropyl-N-methyl-1H-1,2,4-triazol-3-amine was hydrogenated in the presence of 10% Pd on carbon to give 246 after reverse phase HPLC. LCMS: 325.2

Sources & evidence

ORD record
ord-81d915472f9f46c899380756b04d02dc
Source dataset
uspto-grants-2013_01
Patent number
US08343955B2

Reaction notes

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