Hydrochloric Acid → 5-Amino-2-ethylphenol hydrochloride

Participants

Reaction Conditions

Reaction Steps

N-(4-Ethyl-3-hydroxyphenyl)acetamide (3.5 g, 19.5 mmol) was suspended in 5N hydrochloric acid, and the suspension was stirred with heating at 100° C. for 2 hr. The reaction mixture was cooled to room temperature, and the yielded crystals were collected by filtration, and air-dried to give the title compound (2.66 g, 79%) as pale-gray crystals.

Provenance & Evidence