Tetrahydrofuran → HCID 57387079, compound

Participants

Reaction Steps

To a solution of the above-mentioned crude product tert-butyl{3-[(5-nitropyridin-2-yl)oxy]phenyl}carbamate in ethanol (80 mL)/tetrahydrofuran (20 mL) was added 10% palladium-carbon (1.54 g), and the mixture was stirred at room temperature for 7 hr under a hydrogen atmosphere (1.0 pressure). The insoluble material was filtered off, and the filtrate was concentrated under reduced pressure. The obtained residue was recrystallized from methanol to give the title compound (3.35 g, 77%) as brown crystals.

Provenance & Evidence