Benzeneacetonitrile, 2-fluoro- → HCID 59321374, compound

HRID 1800822Notes

Reaction equation

HRID 1800822 reaction equation
[C:1]([N:5]1[CH2:10][CH2:9][C:8]([CH2:17][NH2:18])([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:7][CH2:6]1)([CH3:4])([CH3:3])[CH3:2].[F:19]C1C=CC=CC=1CC#N>>[C:1]([N:5]1[CH2:6][CH2:7][C:8]([CH2:17][NH2:18])([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[F:19])[CH2:9][CH2:10]1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 67592Benzeneacetonitrile, 2-fluoro-HCID 59321351HCID 59321351, compound

Product 1

HCID 59321374HCID 59321374, compound

Procedure

The title material was prepared as described in the synthesis of (1-tert-butyl-4-phenylpiperidin-4-yl)methanamine (Synthesis of amines, Example H) using 2-(2-fluorophenyl)acetonitrile.

Sources & evidence

ORD record
ord-fd3440ecd310482a9517c49d459fc4b9
Source dataset
uspto-grants-2013_01
Patent number
US08343999B2

Reaction notes

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