HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → HCID 59321390, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | 3-fluoro-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)-N-((4-(pyridin-4-yl)piperidin-4-yl)methyl)picolinamide | HCID 59321425 | — |
| Product | HCID 59321390 | HCID 59321390 | — |
Reaction Steps
Following the procedure given for example 81, 3-fluoro-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)-N-((4-(pyridin-4-yl)piperidin-4-yl)methyl)picolinamide (compound example 45) was reacted with methyl chloroformate to give the title compound. LC/MS (M+H)+: 594. Ret. time: 1.32 min. (Condition I); analytical HPLC Ret. time: 5.23 min (Condition H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08343999B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-4cff0c718b504842a268c20d93b400d3 |
| Source note | uspto-grants-2013_01 |