HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-((1,1-dimethylethoxy)carbonyl)-2-methyl-alanine → HCID 59321427, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-((1,1-dimethylethoxy)carbonyl)-2-methyl-alanine | HCID 2733845 | — |
| Reactant | 3-Fluoro-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)-N-((4-phenylpiperidin-4-yl)methyl)picolinamide | HCID 25032856 | — |
| Product | HCID 59321427 | HCID 59321427 | — |
Reaction Steps
Following the procedure given for example 94, 3-fluoro-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)-N-((4-phenylpiperidin-4-yl)methyl)picolinamide (compound example 11) was reacted with 2-(tert-butoxycarbonylamino)-2-methylpropanoic acid to give the title compound. LC/MS (M+H)+: 620. Ret. time: 1.35 min. (Condition G); analytical HPLC Ret. time: 6.55 min (Condition Q).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08343999B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-88a055cf83514e8cb9012cccafa4ac75 |
| Source note | uspto-grants-2013_01 |