Azepane → HCID 66777009, compound

Participants

Reaction Steps

1-Methoxyethylazepane was obtained using procedure 1a, from azepane (10.7 g, 0.107 mol) in methanol (50 cm3), 1-bromo-2-methoxyethane (15.0 g, 0.107 mol) and potassium carbonate (15.0 g). After distillation in vacuo (42-44° C., 1.0 mmHg), 1-methoxyethylazepane was obtained as a colourless liquid in ca. 72% yield. δH (500.13 MHz, CDCl3) 3.6 (6H, m), 3.38 (3H, s), 2.68 (2H, t), 1.59 (8H, br m). ESI-MS: m/z=158 [M+H]+ (100). Calcd. for C9H19NO: 158.1545; found: 158.1535.

Provenance & Evidence