Azepane → HCID 66778791, compound

Participants

Reaction Steps

[2-(2-methoxyethoxy)ethyl]azepane was obtained using procedure 1a, from azepane (10.3 g, 0.103 mol) in methanol (50 cm3), 1-bromo-2-(2-methoxy-ethoxy)ethane (10.0 g, 0.103 mol) and potassium carbonate (16.0 g). After distillation in vacuo (66-68° C., 1.0 mmHg), [2-(2-methoxyethoxy)ethyl]azepane was obtained as a colourless liquid in ca. 65% yield. δH (500.13 MHz, CDCl3) 3.59 (6H, m), 3.38 (3H, s), 2.73 (2H, t), 2.68 (4H, m), 1.59 (8H, br m). ESI-MS: m/z=202 [M+H]+ (100). Calcd. for C11H23NO2: 202.1807; found: 202.1802.

Provenance & Evidence