HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acrylate → 3-(7-bromo-2-oxo-2H-quinolin-1-yl)-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Reactant | 7-Bromoquinolin-2(1H)-one | HCID 14221025 | — |
| Product | 3-(7-bromo-2-oxo-2H-quinolin-1-yl)-propionic acid ethyl ester | HCID 68630048 | 94% |
Reaction Steps
The compound was obtained according to procedure H starting from 7-bromoquinolin-2(1H)-one (commercial; 561 mg, 2.5 mmol) and ethyl acrylate (0.27 mL, 2.5 mmol, 1 eq.). The crude orange oil (0.76 g; 94% yield) was used as such in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08349826B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-7b1c6348d79747fa8a461d16bfc9ffa5 |
| Source note | uspto-grants-2013_01 |