HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-BOC-ethylenediamine → [2-(6-Methoxy-3-nitro-pyridin-2-ylamino)-ethyl]carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-BOC-ethylenediamine | HCID 187201 | — |
| Reactant | 2-Chloro-6-methoxy-3-nitropyridine | HCID 2795029 | — |
| Product | [2-(6-Methoxy-3-nitro-pyridin-2-ylamino)-ethyl]carbamic acid tert-butyl ester | HCID 68631185 | 59% |
Reaction Steps
Starting from 2-chloro-6-methoxy-3-nitropyridine (5.0 g; commercial) and N-Boc-ethylenediamine (4.15 mL; commercial), and proceeding in analogy to Example 17, step 17.i, the title compound was obtained as a yellow solid (4.79 g; 59% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08349826B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-dc4f139e62204eeb8032f1a9324e485c |
| Source note | uspto-grants-2013_01 |