Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 3-(Chloromethyl)-9h-pyrido[3,4-b]indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3-Hydroxymethyl-beta-carboline | HCID 5353338 | — |
| 생성물 | 3-(Chloromethyl)-9h-pyrido[3,4-b]indole | HCID 20148409 | — |
반응 단계
The 3-(hydroxymethyl)-β-carboline was added to an excess (3 grams) of thionyl chloride and the mixture was refluxed for 1 hour. The excess thionyl chloride was then evaporated and the obtained residue was crystallized from hexane. 2.5 grams of 3-(chloromethyl)-β-carboline was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08349850B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-5c3747e1672c4507b59c422a03b60acf |
| 출처 메모 | uspto-grants-2013_01 |