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HRID1801781

反应详情

EQUATION

反应方程式

HRID 1801781 的结构方程式

REACTANTS

反应物

2
结构：NS(=O)(=O)c1cccc(C(=O)O)c1
HCID229352

3-sulfamoylbenzoic acid

C7H7NO4S

结构：N=C(NO)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12
HCID178513391

未命名化合物

PRODUCTS

生成物

1
结构：NS(=O)(=O)c1cccc(-c2nc(-c3cnn4c(C(F)(F)F)cc(-c5ccc(C(F)(F)F)cc5)nc34)no2)c1
HCID16068878

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from N-hydroxy-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxamidine (example B.1) (195 mg, 0.5 mmol) and commercially available 3-sulfamoyl-benzoic acid (101 mg, 0.5 mmol) according to general procedure II. Obtained after purification by flash chromatography (ethyl acetate/heptane) and crystallization (dichloromethane) as a yellow solid (144 mg, 52%). MS (ISN) 553.3 [(M−H)−]; mp 285° C.

WORKUP

后处理

  1. customObtained
  2. customafter purification
  3. customby flash chromatography (ethyl acetate/heptane) and crystallization (dichloromethane) as a yellow solid (144 mg, 52%)