HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline → HCID 178517771, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline | HCID 72942927 | — |
| Reactant | HCID 178422977 | HCID 178422977 | — |
| Product | HCID 178517771 | HCID 178517771 | 95% |
Reaction Steps
4-Chloro-2-(difluoro(4-fluorophenyl)methyl)quinazoline was obtained according to the procedure described in Example 26 for preparation of 4-chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline, substituting 2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazolin-4-ol in Example 26 with 2-(difluoro(4-fluorophenyl)methyl)quinazolin-4-ol (95% yield). LC-MS (ESI) m/z 308 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08349851B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-3421babc1f2241aa836ba222080b6939 |
| Source note | uspto-grants-2013_01 |