HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → HCID 54740910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | HCID 57742965 | HCID 57742965 | — |
| Reactant | HCID 67407936 | HCID 67407936 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 54740910 | HCID 54740910 | — |
Reaction Steps
Methyl 4-(6-cyclohexenyl-4-hydroxy-1-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)-4-oxobutanoate. The title compound is prepared by Palladium mediated Heck cross coupling reaction of cyclohexene and methyl 4-(4-hydroxy-6-iodo-1-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)-4-oxobutanoate (Method 4) according to the procedure set forth in Heck, R. F.; Nolley, J. P. J. Org. Chem., 37, 2320-22 (1971).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08349868B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-ea2c3e4023c74a8891a11536dc9542ea |
| Source note | uspto-grants-2013_01 |