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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1802029Generated: November 1, 2026

4-(3-methyl-1H-pyrazol-1-yl)aniline → 2-((1R,2S)-2-aminocyclohexylamino)-4-(4-(3-methyl-1H-pyrazol-1-yl)phenylamino)pyrimidine-5-carboxamide

https://huagongshe.com/reaction/1802029

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-methyl-1H-pyrazol-1-yl)anilineHCID 350327—
Reactant2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamideHCID 46184612—
Product2-((1R,2S)-2-aminocyclohexylamino)-4-(4-(3-methyl-1H-pyrazol-1-yl)phenylamino)pyrimidine-5-carboxamideHCID 46184609—

Reaction Steps

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 4-(3-methyl-1H-pyrazol-1-yl)aniline in step 1. MS: 407.5 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08349860B2
Source datasetuspto-grants-2013_01
ORD IDord-05f63d538b0a4548abcc821b571b2294
Source noteuspto-grants-2013_01