HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57471974, compound → HCID 57471975, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57471974 | HCID 57471974 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 57471975 | HCID 57471975 | — |
Reaction Steps
A solution of tert-butyl 2-(4-(2-((1R,2S)-2-aminocyclohexylamino)-5-carbamoylpyrimidin-4-ylamino)phenoxy)acetate racemate (180 mg, 0.395 mmol) in TFA (4 mL) was stirred at room temperature for 2 h. It was then concentrated in vacuo. The residue was purified by HPLC to give the titled compound (60 mg). MS 401.2 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08349860B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-c052bca5e6e2473c9bb3f944c06c1f20 |
| Source note | uspto-grants-2013_01 |