Azetidine → HCID 57378960, compound

Participants

Reaction Steps

The product was prepared in the same manner as described in example 3 using 5-(2-(2-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-7-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid (75 mg, 191 μmol) and azetidine (51.5 μl, 765 μmol) as starting materials. The reaction affords 4-(azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid [2-(2-methoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-amide (36.6 mg, 44.4%) off-white solid. mp.: 258.1° C., MS: m/z=432.3 (M+H+).

Provenance & Evidence