4-(Ethoxycarbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid → HCID 67774601, compound

Participants

Reaction Steps

The product was prepared in the same manner as described in example 28 using 2-(3-fluorophenyl)-[1,2,4]triazolo[1,5-a]pyridin-7-amine (580 mg, 2.54 mmol) and 4-(ethoxycarbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid (604 mg, 3.05 mmol) as starting materials. The reaction affords 5-[2-(3-fluoro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-7-ylcarbamoyl]-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester (600 mg, 57.8%) as white solid. mp.: 246-249° C., MS: m/z=409.3 (M+H+).

Provenance & Evidence