Pyrrolidine → HCID 86666029, compound

Participants

Reaction Steps

The product was prepared in the same manner as described in example 70f using 5-(2-((2-fluoroethyl)(methyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-7-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid (100 mg, 277 μmol) and pyrrolidine (68.7 μl, 830 μmol) as starting materials. The reaction affords 2-methyl-4-(pyrrolidine-1-carbonyl)-2H-pyrazole-3-carboxylic acid {2-[(2-fluoro-ethyl)-methyl-amino]-[1,2,4]triazolo[1,5-a]pyridin-7-yl}-amide (96.8 mg, 84.4%) as white solid. MS: m/z=415.0 (M+H+).

Provenance & Evidence