Azetidine → HCID 67968033, compound

Participants

Reaction Steps

The product was prepared in the same manner as described in example 70f using 5-(2-(cyclopropyl(methyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-7-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid (70 mg, 197 μmol) and azetidine (52.9 μl, 788 μmol) as starting materials. The reaction affords 4-(azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid [2-(cyclopropyl-methyl-amino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-amide (65 mg, 83.7%) as off-white solid. mp: 229.6, MS: m/z=395.0 (M+H+).

Provenance & Evidence