Aniline, 2,6-dichloro-4-iodo- → 9-Bromo-1-chloro-N-(2,6-dichloro-4-iodophenyl)benzo[c]-2,6-naphthyridin-5-amine

HRID 1802477Notes

Reaction equation

HRID 1802477 reaction equation
[Br:1][C:2]1[CH:17]=[CH:16][C:5]2[N:6]=[C:7](Cl)[C:8]3[C:13]([C:4]=2[CH:3]=1)=[C:12]([Cl:14])[N:11]=[CH:10][CH:9]=3.[Cl:18][C:19]1[CH:25]=[C:24]([I:26])[CH:23]=[C:22]([Cl:27])[C:20]=1[NH2:21]>>[Br:1][C:2]1[CH:17]=[CH:16][C:5]2[N:6]=[C:7]([NH:21][C:20]3[C:19]([Cl:18])=[CH:25][C:24]([I:26])=[CH:23][C:22]=3[Cl:27])[C:8]3[C:13]([C:4]=2[CH:3]=1)=[C:12]([Cl:14])[N:11]=[CH:10][CH:9]=3

Participants

3

Reactant 2

HCID 12770Aniline, 2,6-dichloro-4-iodo-HCID 59436075HCID 59436075, compound

Product 1

HCID 594359979-Bromo-1-chloro-N-(2,6-dichloro-4-iodophenyl)benzo[c]-2,6-naphthyridin-5-amine

Procedure

The title compound was prepared according to the procedure in (Example 3, Method C, Step 4) using 9-bromo-1,5-dichlorobenzo[c]-2,6-naphthyridine and 2,6-dichloro-4-iodoaniline as the starting materials.

Sources & evidence

ORD record
ord-ae6ba47808344cffae01d6dbcf139d62
Source dataset
uspto-grants-2013_01
Patent number
US08349865B2

Reaction notes

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