Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1802826Generated: October 27, 2026

1-Phenyl-2-(trimethylsilyl)acetylene → 7-nitro-3-phenyl-2-trimethylsilanyl-1H-indole-5-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1802826

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Phenyl-2-(trimethylsilyl)acetyleneHCID 137464—
ReactantBenzoic acid, 4-amino-3-nitro-, ethyl esterHCID 3018687—
Product7-nitro-3-phenyl-2-trimethylsilanyl-1H-indole-5-carboxylic acid ethyl esterHCID 68636197—

Reaction Steps

4-Amino-3-nitro-benzoic acid ethyl ester and trimethyl-phenylethynyl-silane were reacted according to the same procedures as Preparation 19 to give 7-nitro-3-phenyl-2-trimethylsilanyl-1H-indole-5-carboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08349885B2
Source datasetuspto-grants-2013_01
ORD IDord-849af44b5eae410184d86df143d9631b
Source noteuspto-grants-2013_01