huagongshe.com
HRID1802839

反应详情

EQUATION

反应方程式

HRID 1802839 的结构方程式

REACTANTS

反应物

1
结构：O=S(=O)(Cl)c1ccc(Br)cc1F
HCID2736310

4-Bromo-2-fluorobenzenesulfonyl chloride

C6H3BrClFO2S

PRODUCTS

生成物

1
结构：O=S(=O)(c1ccccc1)c1ccc(Br)cc1F
HCID67374087

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Cl][Fe]([Cl])[Cl]
催化剂HCID24380

未命名化合物

结构：c1ccccc1
溶剂HCID241

Benzene

C6H6

PROCEDURE

实验过程

4-Bromo-2-fluoro-benzenesulfonyl chloride (2 g), benzene (1.3 ml) and iron (III) chloride (35 mg) were heated in a sealed tube using a microwave at 200 Watts for 15 seconds. After cooling purification by flash column chromatography (eluent 20% EtOAc/Hexane) gave the subtitle compound as a solid, yield 1.8 g.

WORKUP

后处理

  1. customfor 15 seconds
  2. temperatureAfter cooling
  3. custompurification by flash column chromatography (eluent 20% EtOAc/Hexane)