HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-Tosyloxypropionic acid methyl ester → methyl (2S)-2-{[3'-chloro-5-fluoro-4'-(phenylsulfonyl)biphenyl-2-yl]oxy}propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-Tosyloxypropionic acid methyl ester | HCID 12884153 | — |
| Reactant | 3'-Chloro-5-fluoro-4'-(phenylsulfonyl)biphenyl-2-ol | HCID 67240365 | — |
| Product | methyl (2S)-2-{[3'-chloro-5-fluoro-4'-(phenylsulfonyl)biphenyl-2-yl]oxy}propanoate | HCID 67239082 | — |
Reaction Steps
The subtitle compound was prepared by the method of example 11 step (vii) using the product of step (iii) and the product of example 11 step (vi).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08349897B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-cc06eb3c1dbe401f807b3fd42c656728 |
| Source note | uspto-grants-2013_01 |