3-Thiophenecarboxaldehyde → HCID 66874235, compound

HRID 1802984Notes

Reaction equation

HRID 1802984 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([CH:6]=O)=[CH:2]1.[Br-].[C:9]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)([OH:11])=[O:10]>>[S:1]1[CH:5]=[CH:4][C:3]([CH:6]=[CH:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][C:9]([OH:11])=[O:10])=[CH:2]1

Participants

3

Reactant 2

HCID 681353-ThiophenecarboxaldehydeHCID 10918084Phosphonium, (8-carboxyoctyl)triphenyl-, bromide

Product 1

HCID 66874235HCID 66874235, compound

Procedure

Reaction of 3-thiophenecarboxaldehyde with (8-carboxy-octyl)-triphenyl-phosphonium bromide, in analogy with intermediate 22, step 2, produced 10-(thiophen-3-yl)-dec-9-enoic acid.

Sources & evidence

ORD record
ord-f127530b98eb4c45aa3b52a0a91b118b
Source dataset
uspto-grants-2013_01
Patent number
US08349893B2

Reaction notes

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