Hydrochloric Acid → HCID 58426154, compound

Participants

Reaction Conditions

Reaction Steps

Dimethyl 2-(2-chloro-1,1,2-trifluoro-2-(perfluoropropoxy)ethoxy)terephthalate as prepared in Example 6 (50.00 g, 0.35 mol) was added to a solution of water (726 mL) and potassium hydroxide (KOH, 56.95 g) in a reaction flask. The resulting solution in the reaction flask was heated to reflux overnight, cooled to room temperature (about 25° C.) and then acidified to a pH of ˜1 by adding concentrated HCl until a precipitate formed. The resulting precipitate was filtered and dried under vacuum. Proton NMR of this material showed the desired material, 2-(2-chloro-1,1,2-trifluoro-2-(perfluoropropoxy)ethoxy)terephthalic acid.

Provenance & Evidence