1,4-Dioxane → 6-[2-(tert-Butoxycarbonyl)-2,7-diazaspiro[3.5]nonan-7-yl]-4-(5-methyl-1H-pyrazol-3-ylamino)-2-[2-{3-(pyrid-2-yl)isoxazol-5-yl}pyrrolidin-1-yl]pyrimidine
Reaction equation
[C:31]([CH3:32])([CH3:33])([CH3:34])[O:35][C:36](=[O:37])[N:38]1[CH2:39][C:40]2([CH2:41]1)[CH2:42][CH2:43][NH:44][CH2:45][CH2:46]2.[CH2:47]1[O:48][CH2:49][CH2:50][O:51][CH2:52]1.[Cl:1][c:2]1[cH:3][c:4]([NH:24][c:25]2[cH:26][c:27]([CH3:30])[n:28][nH:29]2)[n:5][c:6]([N:8]2[CH:9]([c:13]3[cH:14][c:15](-[c:18]4[n:19][cH:20][cH:21][cH:22][cH:23]4)[n:16][o:17]3)[CH2:10][CH2:11][CH2:12]2)[n:7]1>>[c:2]1([N:44]2[CH2:43][CH2:42][C:40]3([CH2:39][N:38]([C:36]([O:35][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:37])[CH2:41]3)[CH2:46][CH2:45]2)[cH:3][c:4]([NH:24][c:25]2[cH:26][c:27]([CH3:30])[nH:28][n:29]2)[n:5][c:6]([N:8]2[CH:9]([c:13]3[cH:14][c:15](-[c:18]4[n:19][cH:20][cH:21][cH:22][cH:23]4)[n:16][o:17]3)[CH2:10][CH2:11][CH2:12]2)[n:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a3ff092f3ef44e27b5de688d88be99d1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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