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HRID1803969

反应详情

EQUATION

反应方程式

HRID 1803969 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1COC(=O)N1
HCID2734858

(R)-4-Methyloxazolidin-2-one

C4H7NO2

结构：O=C(c1ccc(Cl)cc1)C1CCN(C(=O)c2ccc(Br)nc2)CC1
HCID58484839

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCC(C(=O)c3ccc(Cl)cc3)CC2)cn1
HCID54755117

未命名化合物

收率 41.8%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 31 and using (6-bromopyridin-3-yl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanone (2 g) described in Preparation Example 23 and (R)-4-methyloxazolidin-2-one (288 mg) described in Preparation Example 25, the title compound (510 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 31
  3. customdescribed in Preparation Example 25