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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1803973Generated: October 26, 2026

Ethyl 4-iodobenzoate → (R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid

https://huagongshe.com/reaction/1803973

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-iodobenzoateHCID 142891—
Reactant(R)-4-Methyloxazolidin-2-oneHCID 2734858—
Product(R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acidHCID 58484719—

Reaction Steps

By reaction and treatment in the same manner as in Preparation Example 18 and using ethyl 4-iodobenzoate (1.4 mL) and (R)-4-methyloxazolidin-2-one (860 mg) described in Preparation Example 25, the title compound (0.9 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-e84e8c1253ee489a82819b91954e3aab
Source noteuspto-grants-2013_01