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HRID1804007

反应详情

EQUATION

反应方程式

HRID 1804007 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)c1cc(Br)ccc1C(=O)O
HCID2761057

4-Bromo-2-(methylsulfonyl)benzoic acid

C8H7BrO4S

结构：Cc1cnc(N2CCNCC2)c(C)c1
HCID58484496

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3S(C)(=O)=O)CC2)c(C)c1
HCID58484505

未命名化合物

收率 68.4%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 60 and using 4-bromo-2-methanesulfonylbenzoic acid (2.79 g) and 1-(3,5-dimethylpyridin-2-yl)piperazine (1.91 g) described in Preparation Example 47, the title compound (3.09 g) was obtained. MS (ESI) m/z:452(M+H)+.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 60
  3. customdescribed in Preparation Example 47