huagongshe.com
HRID1804017

反应详情

EQUATION

反应方程式

HRID 1804017 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc(Br)c(Cl)c1
HCID12594302

4-Bromo-3-chlorobenzoic acid

C7H4BrClO2

结构：Cc1cnc(N2CCNCC2)c(C)c1.Cl
HCID67381379

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(N2CCN(C(=O)c3ccc(Br)c(Cl)c3)CC2)c(C)c1
HCID58484487

未命名化合物

收率 99.1%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 69 and using 4-bromo-3-chlorobenzoic acid (989 mg) and 1-(3,5-dimethylpyridin-2-yl)piperazine hydrochloride (956 mg) described in Preparation Example 64, the title compound (1.7 g) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 69
  3. customdescribed in Preparation Example 64