Ethyl 4-iodobenzoate → HCID 58484603, compound

HRID 1804022Notes

Reaction equation

HRID 1804022 reaction equation
I[C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][CH:3]=1.[C:13]1([C@@H:19]2[CH2:23][O:22][C:21](=[O:24])[NH:20]2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[O:24]=[C:21]1[N:20]([C:2]2[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][CH:3]=2)[C@H:19]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:23][O:22]1

Participants

3

Reactant 2

HCID 142891Ethyl 4-iodobenzoateHCID 730425(4R)-4-phenyl-1,3-oxazolidin-2-one

Product 1

HCID 58484603HCID 58484603, compound

Procedure

By reaction and treatment in the same manner as in Preparation Example 12 and using ethyl 4-iodobenzoate (1.7 mL) and (R)-(−)-4-phenyloxazolidin-2-one (2 g), the title compound (4 g) was obtained.

Workup

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 12

Sources & evidence

ORD record
ord-9d7d8c7981254c26bb2828658072f3ce
Source dataset
uspto-grants-2013_01
Patent number
US08354401B2

Reaction notes

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