Ethyl 4-iodobenzoate → HCID 58484825, compound

HRID 1804027Notes

Reaction equation

HRID 1804027 reaction equation
I[C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8]CC)=[O:7])=[CH:4][CH:3]=1.[CH:13]([C@H:16]1[CH2:20][O:19][C:18](=[O:21])[NH:17]1)([CH3:15])[CH3:14]>>[CH:13]([C@H:16]1[CH2:20][O:19][C:18](=[O:21])[N:17]1[C:2]1[CH:3]=[CH:4][C:5]([C:6]([OH:8])=[O:7])=[CH:11][CH:12]=1)([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 142891Ethyl 4-iodobenzoateHCID 7157133(4S)-4-(propan-2-yl)-1,3-oxazolidin-2-one

Product 1

HCID 58484825HCID 58484825, compound

Procedure

By reaction and treatment in the same manner as in Preparation Example 18 and using ethyl 4-iodobenzoate (2.9 mL) and (S)-4-isopropyloxazolidin-2-one (2.5 g), the title compound (4.5 g) was obtained.

Workup

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 18

Sources & evidence

ORD record
ord-deb6650d307e44c9824abe1a5c7f1272
Source dataset
uspto-grants-2013_01
Patent number
US08354401B2

Reaction notes

Loading…