2-Oxazolidinone → 3-{5-Chloro-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one

Participants

Role	Name	HCID	Charge
Reactant	2-Oxazolidinone	HCID 73949	—
Reactant	(2-Bromo-4-chlorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone	HCID 58484730	—
Product	3-{5-Chloro-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one	HCID 54755234	56.4%

Reaction Steps

By reaction and treatment in the same manner as in Preparation Example 12 and using (2-bromo-4-chlorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (1.79 g) described in Preparation Example 119 and oxazolidin-2-one (0.381 g), the title compound (1.023 g) was obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08354401B2
Source dataset	uspto-grants-2013_01
ORD ID	ord-87440c769e334ff89b07c5bf1f2240c8
Source note	uspto-grants-2013_01