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HRID1804072

反应详情

EQUATION

反应方程式

HRID 1804072 的结构方程式

REACTANTS

反应物

2
结构：Cc1cnc(N2CCN(C(=O)c3ccc(Cl)cc3Br)CC2)c(C)c1
HCID58484730

未命名化合物

结构：CC1CCS(=O)(=O)N1
HCID67380814

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(N2CCN(C(=O)c3ccc(Cl)cc3N3[C@H](C)CCS3(=O)=O)CC2)c(C)c1
HCID58484709

未命名化合物

收率 20.6%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 12 and using (2-bromo-4-chlorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (408.7 mg) described in Preparation Example 119 and 3-methylisothiazolidine-1,1-dioxide (135 mg), the title compound (95.1 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 12