huagongshe.com
HRID1804073

反应详情

EQUATION

反应方程式

HRID 1804073 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)N1CCNC1=O
HCID79350

N-Acetyl-2-imidazolidinone

C5H8N2O2

结构：Cc1cnc(N2CCN(C(=O)c3ccc(Cl)cc3Br)CC2)c(C)c1
HCID58484730

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)N1CCN(c2cc(Cl)ccc2C(=O)N2CCN(c3ncc(C)cc3C)CC2)C1=O
HCID58484683

未命名化合物

收率 48.6%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 12 and using (2-bromo-4-chlorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (408.7 mg) described in Preparation Example 119 and 1-acetyl-2-imidazolidinone (128 mg), the title compound (221.5 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 12