HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-methylbenzoic acid → (4-Bromo-2-methylphenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-methylbenzoic acid | HCID 99570 | — |
| Reactant | 1-(5-Ethyl-3-methylpyridin-2-yl)piperazine | HCID 58484578 | — |
| Product | (4-Bromo-2-methylphenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484569 | 56.7% |
Reaction Steps
By reaction and treatment in the same manner as in Preparation Example 60 and using 4-bromo-2-methylbenzoic acid (1.00 g) and 1-(5-ethyl-3-methylpyridin-2-yl)piperazine (1.05 g) described in Preparation Example 53, the title compound (1.06 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354401B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-00d92638033d43d8913cfed3c97393a8 |
| Source note | uspto-grants-2013_01 |