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HRID1804081

反应详情

EQUATION

反应方程式

HRID 1804081 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(N2CCNCC2)c(C)c1
HCID70544

1-(2,4-Xylyl)piperazine

C12H18N2

结构：Cc1cc(F)ncc1C(=O)O
HCID46739274

6-Fluoro-4-methylpyridine-3-carboxylic acid

C7H6FNO2

PRODUCTS

生成物

1
结构：Cc1ccc(N2CCN(C(=O)c3cnc(F)cc3C)CC2)c(C)c1
HCID58484738

未命名化合物

收率 83.3%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 60 and using 6-fluoro-4-methylnicotinic acid (500 mg) and 1-(2,4-dimethylphenyl)piperazine (607 mg), the title compound (870 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 60