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HRID1804085

反应详情

EQUATION

反应方程式

HRID 1804085 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(F)ncc1C(=O)O
HCID46739274

6-Fluoro-4-methylpyridine-3-carboxylic acid

C7H6FNO2

结构：c1nc(N2CCNCC2)c(C2CC2)cc1C1CC1
HCID58484701

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(F)ncc1C(=O)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1
HCID58484583

未命名化合物

收率 85.3%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 60 and using 6-fluoro-4-methylnicotinic acid (600 mg) and 1-(3,5-dicyclopropylpyridin-2-yl)piperazine (922 mg) described in Preparation Example 62, the title compound (1.23 g) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 60
  3. customdescribed in Preparation Example 62