HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(3,5-Dimethylpyridin-2-yl)piperazine → 5-Bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(3,5-Dimethylpyridin-2-yl)piperazine | HCID 58484496 | — |
| Edukt | 4-Bromo-2-cyanobenzoic acid | HCID 58484585 | — |
| Produkt | 5-Bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile | HCID 58484628 | 83,1% |
Reaktionsschritte
By reaction and treatment in the same manner as in Preparation Example 90 and using 4-bromo-2-cyanobenzoic acid (2.03 g) described in Preparation Example 192 and 1-(3,5-dimethylpyridin-2-yl)piperazine (1.81 g) described in Preparation Example 47, the title compound (2.98 g) was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08354401B2 |
| Quelldatensatz | uspto-grants-2013_01 |
| ORD ID | ord-4c5d319daa99497f98bc75f7eec95ff2 |
| Quellennotiz | uspto-grants-2013_01 |