huagongshe.com
HRID1804137

反应详情

EQUATION

反应方程式

HRID 1804137 的结构方程式

REACTANTS

反应物

2
结构：N#Cc1cc(Br)ccc1C(=O)O
HCID58484585

4-Bromo-2-cyanobenzoic acid

C8H4BrNO2

结构：Cc1cc(C2CC2)cnc1N1CCNCC1
HCID58484718

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)cc2C#N)CC1
HCID58484573

未命名化合物

收率 82.2%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 90 and using 4-bromo-2-cyanobenzoic acid (2.14 g) described in Preparation Example 192 and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine (2.16 g) described in Preparation Example 96, the title compound (3.31 g) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 90
  3. customdescribed in Preparation Example 96