(S)-4-Benzyl-2-oxazolidinone → HCID 58484545, compound

HRID 1804140Notes

Reaction equation

HRID 1804140 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:10]=[CH:9][C:8](B(O)O)=[CH:7][CH:6]=1)=[O:4].[CH2:14]([C@H:21]1[CH2:25][O:24][C:23](=[O:26])[NH:22]1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([C@H:21]1[CH2:25][O:24][C:23](=[O:26])[N:22]1[C:8]1[CH:9]=[CH:10][C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:6][CH:7]=1)[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 736225(S)-4-Benzyl-2-oxazolidinoneHCID 27343694-Methoxycarbonylphenylboronic acid

Product 1

HCID 58484545HCID 58484545, compoundYield 6.7%

Procedure

By reaction and treatment in the same manner as in Preparation Example 22 and using p-(methoxycarbonyl)phenylboronic acid (2.45 g) and (S)-4-benzyloxazolidin-2-one (1.205 g), the title compound (0.142 g) was obtained.

Workup

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 22

Sources & evidence

ORD record
ord-d72ed44d60ae488db7622cf0748897e6
Source dataset
uspto-grants-2013_01
Patent number
US08354401B2

Reaction notes

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